Published on in Vol 27 (2025)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/60630, first published .
Impact of Mobile Phone Usage on Sleep Quality Among Medical Students Across Latin America: Multicenter Cross-Sectional Study

Impact of Mobile Phone Usage on Sleep Quality Among Medical Students Across Latin America: Multicenter Cross-Sectional Study

Impact of Mobile Phone Usage on Sleep Quality Among Medical Students Across Latin America: Multicenter Cross-Sectional Study

Original Paper

1One Health Research Group, Universidad de las Américas, Quito, Ecuador

2Grupo de Investigación Bienestar, Salud y Sociedad, Escuela de Psicología y Educación, Universidad de Las Américas, Quito, Ecuador

3Interinstitutional Internal Medicine Group (GIMI 1), Department of Internal Medicine, Universidad Libre, Cali, Colombia

4Facultad de Medicina, Universidad de Panamá, Ciudad de Panamá, Panama

5Facultad de Medicina, Universidad del Pacifico, Asunción, Paraguay

6Facultad de Medicina Humana, Universidad Nacional del Altiplano, Puno, Peru

7Facultad de Ciencias de la Salud, Universidad Privada Franz Tamayo, La Paz, Bolivia

8Facultad de Ciencias de la Salud, Universidad del Quindío, Armenia, Colombia

9Facultad de Medicina, Institución Universitaria Visión de las Américas, Pereira, Colombia

10Public Health Department, Bringham Young University, Provo, UT, United States

Corresponding Author:

Esteban Ortiz-Prado, MD, MPH, MSc, PhD

One Health Research Group

Universidad de las Américas

Calle de los Colimes

Quito, 170137

Ecuador

Phone: 593 0995760693

Email: e.ortizprado@gmail.com


Background: The ubiquitous use of mobile phones among medical students has been linked to potential health consequences, including poor sleep quality.

Objective: This study investigates the prevalence of mobile phone addiction and its association with sleep quality among medical students across 6 Latin American countries.

Methods: A descriptive, cross-sectional, multicenter study was conducted between December 2023 and March 2024 using a self-administered online survey. The survey incorporated the Mobile Phone Addiction Scale and the Pittsburgh Sleep Quality Index to evaluate mobile phone addiction and sleep quality among 1677 medical students. A multiple regression model was applied to analyze the relationship between mobile phone addiction and poor sleep quality, adjusting for sex, age, and educational level to ensure robust results.

Results: Mobile phone addiction was identified in 32.5% (545/1677) of participants, with significant differences across countries. The overall mean Pittsburgh Sleep Quality Index score was 7.26, indicating poor sleep quality. Multiple regression analysis revealed a strong association between mobile phone addiction and poor sleep, controlled for demographic variables (β=1.4, 95% CI 1.05-1.74).

Conclusions: This study underscores a significant prevalence of mobile phone addiction among medical students and its detrimental association with sleep quality in Latin America. The findings advocate for the need to address mobile phone usage to mitigate its negative implications on student health and academic performance. Strategies to enhance digital literacy and promote healthier usage habits could benefit medical education and student well-being.

J Med Internet Res 2025;27:e60630

doi:10.2196/60630

Keywords



By 2024, approximately 17.8 billion mobile phones are projected to be in use globally, according to Statista [Forecast number of mobile devices worldwide from 2020 to 2025 (in billions)*. Statista; 2024. URL: https://www.statista.com/statistics/245501/multiple-mobile-device-ownership-worldwide/ [accessed 2024-04-28] 1]. Initially designed for voice communication, mobile phones have evolved into essential tools for text messaging, complex communication, and daily activities [Morgan C. Draw Your Phone: The Cellphone as an Intimate, Everyday Artefact. Newland. Teaching and Learning the Archaeology of the Contemporary Era Bloomsbury Publishing; 2023:101.2]. The advent of smartphones with advanced computational capabilities has further integrated these devices into modern life [De-Sola Gutiérrez J, Rodríguez de Fonseca F, Rubio G. Cell-phone addiction: a review. Front Psychiatry. 2016;7:175. [FREE Full text] [CrossRef] [Medline]3]. While they offer substantial benefits, such as enhanced access to educational and informational resources, excessive use also poses significant risks [Naeem Z. Health risks associated with mobile phones use. Int J Health Sci (Qassim). 2014;8(4):V-VI. [FREE Full text] [Medline]4]. Acute or chronic overuse of mobile phones has been associated with physical issues like headaches, carpal tunnel syndrome, tendinitis, and accidents caused by distraction [Zirek E, Mustafaoglu R, Yasaci Z, Griffiths MD. A systematic review of musculoskeletal complaints, symptoms, and pathologies related to mobile phone usage. Musculoskelet Sci Pract. 2020;49:102196. [CrossRef] [Medline]5]. In addition, excessive use can result in less overt but impactful effects, including reduced motivation, impaired memory and concentration, sleep disturbances, and learning difficulties [Westerman R, Hocking B. Diseases of modern living: neurological changes associated with mobile phones and radiofrequency radiation in humans. Neurosci Lett. 2004;361(1-3):13-16. [CrossRef] [Medline]6].

One of the most well-documented negative consequences of mobile phone usage is its disruption of sleep patterns and quality. Prolonged screen exposure and late-night cellphone use adversely affect both the quantity and quality of sleep [Exelmans L, Van den Bulck J. Bedtime mobile phone use and sleep in adults. Soc Sci Med. 2016;148:93-101. [CrossRef] [Medline]7,White AG, Buboltz W, Igou F. Mobile phone use and sleep quality and length in college students. International Journal of Humanities and Social Science. 2011;1(18):51-58.8]. Poor sleep has been linked to a range of health problems, including cardiovascular diseases, mental health disorders, neurodegenerative conditions, musculoskeletal issues, and a reduced overall quality of life [Ai S, Ye S, Li G, Leng Y, Stone KL, Zhang M, et al. Association of disrupted delta wave activity during sleep with long-term cardiovascular disease and mortality. J Am Coll Cardiol. 2024;83(17):1671-1684. [CrossRef] [Medline]9,Addo PNO, Mundagowa PT, Zhao L, Kanyangarara M, Brown MJ, Liu J. Associations between sleep duration, sleep disturbance and cardiovascular disease biomarkers among adults in the United States. BMC Public Health. 2024;24(1):947. [FREE Full text] [CrossRef] [Medline]10]. University students, particularly those belonging to Generation Z (Gen Z), also known as iGen or postmillennials, face compounded risks. Born between 1996 and 2015, Gen Z is the first generation to grow up with the internet and portable digital technology. These “digital natives” excel in mobile phone use and social media interaction but have less experience with traditional communication methods, such as print media. For medical students, the demands of their academic schedules, combined with excessive mobile phone usage, pose risks to mental health, sleep quality, and academic performance [Almutairi H, Alsubaiei A, Abduljawad S, Alshatti A, Fekih-Romdhane F, Husni M, et al. Prevalence of burnout in medical students: a systematic review and meta-analysis. Int J Soc Psychiatry. 2022;68(6):1157-1170. [CrossRef] [Medline]11].

In recent years, mobile phones have become indispensable tools in the academic training of medical students [Machleid F, Kaczmarczyk R, Johann D, Balčiūnas J, Atienza-Carbonell B, von Maltzahn F, et al. Perceptions of digital health education among european medical students: mixed methods survey. J Med Internet Res. 2020;22(8):e19827. [FREE Full text] [CrossRef] [Medline]12]. Originally designed for personal communication, these devices have evolved into essential academic resources, facilitating learning and collaboration. However, this transition has also been associated with dependency and excessive use, raising concerns about potential addiction [Li S, Feng N, Cui L. Network analysis of social anxiety and problematic mobile phone use in Chinese adolescents: a longitudinal study. Addict Behav. 2024;155:108026. [CrossRef] [Medline]13]. Constant internet connectivity provided by smartphones fosters engagement not only with educational resources but also with addictive behaviors and content [De-Sola Gutiérrez J, Rodríguez de Fonseca F, Rubio G. Cell-phone addiction: a review. Front Psychiatry. 2016;7:175. [FREE Full text] [CrossRef] [Medline]3]. These include compulsive information seeking, excessive use of online games and shopping platforms, and problematic online interactions such as cybersexuality and cybercontacts [Seoane HA, Moschetto L, Orliacq F, Orliacq J, Serrano E, Cazenave MI, et al. Sleep disruption in medicine students and its relationship with impaired academic performance: a systematic review and meta-analysis. Sleep Med Rev. 2020;53:101333. [CrossRef] [Medline]14]. For medical students, in particular, problematic smartphone use, nomophobia (a fear of not having mobile phone connectivity), and general dependency not only negatively impacts academic performance but also poses significant health risks [Rozgonjuk D, Saal K, Täht K. Problematic smartphone use, deep and surface approaches to learning, and social media use in lectures. Int J Environ Res Public Health. 2018;15(1):92. [FREE Full text] [CrossRef] [Medline]15-Copaja-Corzo C, Aragón-Ayala CJ, Taype-Rondan A, Nomotest-Group N. Nomophobia and its associated factors in peruvian medical students. Int J Environ Res Public Health. 2022;19(9):5006. [FREE Full text] [CrossRef] [Medline]18].

Recent studies in the United States and Turkey have identified a correlation between increased mobile phone use and poor sleep quality among university and medical students [Kaya F, Bostanci Daştan N, Durar E. Smart phone usage, sleep quality and depression in university students. Int J Soc Psychiatry. 2021;67(5):407-414. [CrossRef] [Medline]19,Herrell C, Foster S. Can't stop won't stop: problematic phone use, sleep quality, and mental health in U.S. graduate students. J Am Coll Health. 2024;28:1-7. [CrossRef] [Medline]20]. A meta-analysis further highlighted that sleep quality is closely linked to academic performance in medical students, emphasizing the need for interventions to address this issue [Seoane HA, Moschetto L, Orliacq F, Orliacq J, Serrano E, Cazenave MI, et al. Sleep disruption in medicine students and its relationship with impaired academic performance: a systematic review and meta-analysis. Sleep Med Rev. 2020;53:101333. [CrossRef] [Medline]14]. Despite this growing body of evidence, research on the impact of mobile phone addiction on sleep quality among medical students in Latin America remains limited.

Medical students in Latin America face unique challenges, including demanding schedules, irregular sleep patterns, and high stress levels, which may make them particularly vulnerable to mobile phone addiction. In addition, the reliance on mobile phones for communication and education in resource-limited health care education systems could exacerbate these issues.

This study aims to investigate the prevalence of mobile phone addiction and its association with sleep quality among medical students in 6 Latin American countries. By addressing this gap, we hope to provide insights that can inform targeted interventions to improve the well-being and academic success of medical students in the region.


Study Design

A descriptive, cross-sectional, multicenter study was conducted from December 2023 to March 2024.

Setting and Participants

This study used a self-administered online survey targeting medical students enrolled at universities across 6 Latin American countries: Bolivia, Colombia, Ecuador, Panama, Paraguay, and Peru. Participants included undergraduate students from the first to the final years (sixth or seventh) of their medical degree. Participants were selected using a nonprobability convenience sampling method through the online survey platform SurveyMonkey. Participation was voluntary.

Survey Development and Measures

The research team designed a 49-item anonymous online survey to collect data on demographic characteristics, mobile phone usage, and sleep quality among the Latin American medical student population. An initial version of the questionnaire was reviewed by a public health expert to ensure its relevance, accuracy, and to preempt potential errors. It was then pilot tested with 20 medical students from Ecuador to fine tune comprehension and design; data from this phase were excluded from the final analysis. Revisions after pilot test produced the final version of the survey, which was drafted in Spanish. The report on the online survey used in this research, prepared following the CHERRIES (Checklist for Reporting Results of Internet E-Surveys), is provided in Table S1 in

Multimedia Appendix 1

Checklist for Reporting Results of Internet E-Surveys (CHERRIES).

DOCX File , 18 KBMultimedia Appendix 1.

Questionnaire and Variables

The final version of the questionnaire was structured into 3 sections to meet the research objectives.

Demographic Data

The first section collected demographic information such as sex, age, country of residence, year of study, and type of university, categorized by funding source (public or private). It also included an additional year category (7th year) to account for students in countries such as Colombia and Panama, where medical training can extend up to 13 semesters.

Mobile Phone Addiction

The second section used the Mobile Phone Addiction Scale, designed and validated by Basu et al [Basu S, Garg S, Singh MM, Kohli C. Addiction-like behavior associated with mobile phone usage among medical students in Delhi. Indian J Psychol Med. 2018;40(5):446-451. [FREE Full text] [CrossRef] [Medline]21], which adheres to ICD-10 (International Statistical Classification of Diseases, Tenth Revision) criteria for substance dependence syndrome. It comprised 20 questions rated on a 6-point Likert scale (from 1-completely disagree to 6-completely agree). The questionnaire evaluated 6 addiction components: intense desire, poor control, abstinence, tolerance, diminished interest in alternative pleasures, and harmful use. Addiction presence was defined if half or more of the questions in each component were affirmed; global addiction was noted when three or more components were present.

Sleep Quality

The third section used the standardized Pittsburgh Sleep Quality Index (PSQI) [Buysse DJ, Reynolds CF, Monk TH, Berman SR, Kupfer DJ. The pittsburgh sleep quality index: a new instrument for psychiatric practice and research. Psychiatry Res. 1989;28(2):193-213. [CrossRef] [Medline]22,Hita-Contreras F, Martínez-López E, Latorre-Román PA, Garrido F, Santos MA, Martínez-Amat A. Reliability and validity of the Spanish version of the pittsburgh sleep quality index (PSQI) in patients with fibromyalgia. Rheumatol Int. 2014;34(7):929-936. [CrossRef] [Medline]23], designed to evaluate sleep quality through 19 questions covering 7 components: subjective sleep quality, sleep latency, sleep duration, habitual sleep efficiency, sleep disturbances, use of sleep medication, and daytime dysfunction. Scores ranged from 0 (no difficulty) to 3 (very severe difficulty), with a total score from 0 to 21. A score of 5 or less indicated normal rest, while scores greater than 5 indicated poor rest, categorizing the overall sleep quality level.

Data Collection and Management

The online platform SurveyMonkey was used to facilitate data collection. Participants accessed the survey through a unique link shared across social media channels, including Facebook and WhatsApp (Meta). The preamble of the survey outlined the study’s aims, assured confidentiality, and sought informed consent. Participants were required to agree to the informed consent and accept the participation agreement to proceed, reinforcing the survey’s anonymity. To ensure high data integrity, all responses were meticulously reviewed for potential errors or inconsistencies, such as implausible age ranges or respondents selecting all available answers. This scrutiny led to the exclusion of questionnaires from an original sample of 1798 survey responses before filtering to a final total of 1677 responses which were considered valid and included in the study (Figure 1).

Figure 1. Flowchart of the Strengthening the Reporting of Observational Studies in Epidemiology–based sample selection process for this study.

Bias

To mitigate potential bias during data collection and management, several strategies were used. For example, IP addresses were used to eliminate duplicate submissions by configuring the SurveyMonkey platform to limit 1 response per IP address. To ensure anonymity the questionnaire was carefully curated to avoid collecting any identifiable information, including IP addresses, beyond what was necessary for filtering duplicates. In the analysis phase, additional steps were taken to minimize bias. One of the researchers meticulously reviewed the results, and any discrepancies identified were collaboratively resolved. This rigorous approach ensured that only valid and genuine responses were included in the final analysis, substantially enhancing the reliability and credibility of the study’s findings. The use of a nonprobability convenience sampling method was justified in this study of medical students across 6 Latin American countries due to logistical, resource, and time constraints. This method enabled the inclusion of participants from multiple universities, making the study feasible and cost-effective while capturing valuable insights into issues such as mobile phone addiction and sleep quality. Although convenience sampling introduces potential biases, including selection bias and limited generalizability, it was the most practical option given the difficulty of accessing a more representative sample across diverse regions. Despite these limitations, the approach allowed for timely data collection and provided exploratory insights into the specific challenges faced by medical students.

Statistical Analysis

The current study used descriptive statistical tests to analyze the responses for each categorical variable, including the calculation of frequencies and percentages. For quantitative variables, measures of central tendency (mean) and dispersion (SD) were evaluated.

To evaluate the relationships between the variables studied, inferential statistical tests were used. Chi-square tests were conducted to assess the influence of participant characteristics on the presence of mobile phone addiction. t tests and one-way ANOVA were used to examine the influence of characteristics on sleep quality as determined by mean PSQI scores.

Ordinary least squares (OLS) regression was conducted as part of a multiple regression model adjusted for sex, age, and educational level was used to estimate the association between mobile phone addiction and poor sleep quality, expressed by β and 95% CI. In all statistical analyses, a P value of <.05 was considered statistically significant. All the analysis was conducted using R (R Foundation for Statistical Computing).

Ethical Considerations

This study was conducted in strict adherence to the ethical standards set forth in the Declaration of Helsinki. It also followed the ethical protocols approved by the Ethics Committee of Universidad de Las Américas, under code 2023-EXC-004. The research team was trained to ensure that all aspects of the study upheld the principles of participant anonymity and voluntary participation. No personally identifiable or sensitive information was solicited or included in the research data.


Demographic Characteristics

A total of 1677 medical students from 6 Latin American countries participated in this study. Ecuador and Panama had the highest representations at 20.1% and 18.0%, respectively. The majority of participants were female (1083/1677, 64.4%), and over half (973/1677, 58%) were in their initial years of undergraduate study (1st to 3rd year). The majority (967/1677, 57.7%) were enrolled in private universities (Table 1).

Table 1. Demographic characteristics of medical students from 6 Latin American countries.
CharacteristicsBolivia (n=251Colombia (n=259)Ecuador (n=337)Panama (n=302)Paraguay (n=253)Peru (n=275)Overall (n=1677)
Sex, n (%)

Male99 (39.4)103 (39.8)118 (35)113 (37.4)73 (28.9)88 (32)594 (35.4)

Female152 (60.6)156 (60.2)219 (65)189 (62.6)180 (71.1)187 (68)1083 (64.6)
Age, mean (SD)


20.2 (3.14)21.6 (3.46)21.7 (2.18)22.1 (2.27)23 (4.58)22.3 (3.76)21.8 (3.36)
Year of study, n (%)

First111 (44.2)31 (12)12 (3.6)22 (7.3)67 (26.5)35 (12.7)278 (16.6)

Second104 (41.4)51 (19.7)43 (12.8)52 (17.2)33 (13.0)64 (23.3)347 (20.7)

Third28 (11.2)53 (20.5)124 (36.8)60 (19.9)35 (13.8)48 (17.5)348 (20.8)

Fourth4 (1.6)34 (13.1)124 (36.8)20 (6.6)58 (22.9)38 (13.8)278 (16.6)

Fifth2 (0.8)65 (25.1)14 (4.2)41 (13.6)32 (12.6)33 (12)187 (11.2)

Sixth2 (0.8)18 (6.9)8 (2.4)102 (33.8)20 (7.9)19 (6.9)169 (10.1)

Seventh0 (0)7 (2.7)12 (3.6)5 (1.7)8 (3.2)38 (13.8)70 (4.2)
Level of education, n (%)

Initial (first-third year)243 (96.8)135 (52.1)179 (53.1)134 (44.4)135 (53.4)147 (53.5)973 (58)

Advanced (fourth-seventh year)8 (3.2)124 (47.9)158 (46.9)168 (55.6)118 (46.6)128 (46.5)704 (42)
Type of university, n (%)

Private university248 (98.8)89 (34.4)256 (76%)41 (13.6%)229 (90.5)104 (37.8)967 (57.7)

Public university3 (1.2)170 (65.6)81 (24%)261 (86.4%)24 (9.5)171 (62.2)710 (42.3)

Smartphone Usage

Smartphones were used by nearly the entire study population (1651/1677, 98.4%), with 94.9% (1591/1677) reporting using mobile phones for academic purposes. However, computers or laptops were preferred for studies (797/1677, 47.5%), while mobile phones were the least preferred option for studying (108/1677, 6.4%; Figure 2).

Figure 2. Characteristics of cell phone use, academic preparation, and distribution of cell phone addiction and sleep quality by country of residence among Latin American medical students.

Mobile Phone Addiction

According to the Mobile Phone Addiction Scale, 32.5% (545/1677) of participants exhibited mobile phone addiction. The domain most affected was tolerance to use (974/1677, 58.1%), followed by an intense desire to use the phone (708/1677, 42.2%). A decrease in pleasure was the least common symptom, noted in only 9.8% (165/1677) of the sample (Table S2 in

Multimedia Appendix 1

Checklist for Reporting Results of Internet E-Surveys (CHERRIES).

DOCX File , 18 KBMultimedia Appendix 1).

According to the distribution among the participating countries, the highest prevalence of mobile phone addiction was observed in medical students from Panama (121/302, 40.1%), while the lowest was in Peru (70/253, 25.5%; P<.001; Figure 2). Furthermore, the presence of mobile phone addiction was associated with certain participant characteristics, being significantly higher (38/86, 44.2%) among medical students who stated they did not use their phones for academic purposes (P=.02), as well as among those who reported that their undergraduate preparation negatively affected their rest (448/1251, 35.8%; P<.001). In addition, medical students who preferred printed texts had the lowest percentage of mobile phone addiction (81/302, 22.8%) when compared with those participants using screen devices (mobile phone, computer, and tablet; P=.002; Table 2).

Table 2. Relationship between the characteristics of the participants with mobile phone addiction and sleep quality.
CharacteristicsMobile addictionPSQIa

Absence, n (%)Presence, n (%)P valueMean (SD)P value
Sex

.92
.02

Male (n=594)400 (67.3)194 (32.7)
7.04 (3.34)

Female (n=1083)732 (67.6)351 (32.4)
7.39 (3.5)
Level of education

.85
.22

Initial (n=973)655 (67.3)318 (32.7)
7.37 (3.41)

Advanced (n=704)477 (67.8)227 (32.2)
7.11 (3.5)
Type of university

.58
.001

Private university (n=967)658 (68)309 (32)
7.57 (3.48)

Public university (n=710)474 (66.8)236 (33.2)
6.85 (3.37)
Academic mobile phone use

.02
.72

No (n=86)48 (55.8)38 (44.2)
7.40 (3.5)

Yes (n=1591)1084 (68.1)507 (31.9)
7.26 (3.45)
Preferred way of studying

.002
.02

Mobile phone (n=108)61 (56.5)47 (43.5)
8.21 (3.71)

Computer/laptop (n=797)551 (69.1)246 (30.9)
7.13 (3.41)

Tablet/iPad (n=470)299 (63.6)171 (36.4)
7.22 (3.47)

Prefer printed texts (n=302)221 (73.2)81 (22.8)
7.34 (3.4)
Negative effects of your academic training on your rest

<.001
<.001

No (n=426)329 (77.2)97 (22.8)
6.08 (3.63)

Yes (1251)803 (64.2)448 (35.8)
7.49 (3.37)

aPSQI: Pittsburgh Sleep Quality Index.

Sleep Quality

As measured by the PSQI, a general mean of poor sleep quality of 7.26 (SD 3.45) was found among medical students from the 6 study countries. The components with the highest scores (indicating the worst sleep quality) were subjective sleep quality (1.33, SD 0.77) and daytime dysfunction (1.31, SD 0.84), while the lowest scores were found in the use of sleep medication (0.27, SD 0.70) and habitual sleep efficiency (0.89, SD 1.12; Table 3).

Table 3. Characteristics of the components of sleep quality in medical students in Latin America.
PSQIa valuesBolivia (n=251), mean (SD)Colombia (n=259), mean (SD)Ecuador (n=337), mean (SD)Panama (n=302), mean (SD)Paraguay (n=253), mean (SD)Peru (n=275), mean (SD)Overall (n=1677), mean (SD)
PSQI7.69 (3.61)7.11 (3.43)7.47 (3.31)7.39 (3.49)7.64 (3.52)6.29 (3.22)7.26 (3.45)
Sleep quality components

Subjective sleep quality1.40 (0.87)1.31 (0.75)1.31 (0.69)1.42 (0.74)1.38 (0.8)1.13 (0.75)1.33 (0.77)

Sleep latency1.15 (0.91)1.20 (0.97)1.11 (0.86)1.08 (0.97)1.39 (0.97)0.996 (0.88)1.15 (0.93)

Sleep duration1.33 (1.13)1.09 (1.05)1.23 (1.04)1.23 (1.09)1.01 (1.07)0.924 (1.01)1.14 (1.07)

Habitual sleep efficiency0.95 (1.16)0.76 (1.05)0.88 (1.09)0.96 (1.16)0.97 (1.15)0.79 (1.07)0.89 (1.12)

Sleep disturbance1.31 (0.66)1.18 (0.54)1.26 (0.57)1.04 (0.5)1.21 (0.49)1.16 (0.55)1.19 (0.56)

Use of sleeping medication0.25 (0.6)0.29 (0.73)0.27 (0.72)0.25 (0.68)0.38 (0.86)0.17 (0.55)0.27 (0.7)

Daytime dysfunction1.29 (0.9)1.28 (0.78)1.41 (0.84)1.43 (0.86)1.28 (0.79)1.11 (0.81)1.31 (0.84)

aPSQI: Pittsburgh Sleep Quality Index.

Differences in sleep quality by country showed the highest scores for Bolivian (7.69, SD 3.61) and Paraguayan (7.64, SD 3.52) students, while Peru had the lowest score (6.29, SD 3.22; P<.001). Complementary post hoc analyses revealed that Peruvian medical students had significantly lower PSQI scores (better sleep quality) compared with their counterparts from Bolivia (P<.001), Ecuador (P<.001), Panama (P=.001), and Paraguay (P<.001; Figure 2).

Furthermore, characteristics associated with higher PSQI scores (worse sleep quality) were found in female medical students (7.39, SD 3.5; P=.02), those from private universities (7.57, SD 3.48; P=.001), those who preferentially use mobile phones for studying (8.21, 3.71; P=.02), and those who consider that academic preparation affects their sleep quality (7.49, SD 3.37; P<.001; Table 2).

Effect of Mobile Phone Addiction on Sleep Quality

The negative influence of mobile phone addiction on sleep quality was statistically significant across all seven components of the PSQI, showing higher mean scores (worse quality) in the group of medical students with mobile phone addiction, including in the dimensions of habitual sleep efficiency and use of sleeping medication (Table 4).

Table 4. Effect of mobile phone addiction on the components of sleep quality of medical students in Latin America.
ComponentsMobile addictionP value

Absence (n=1132), mean (SD)Presence (n=545), mean (SD)
Subjective sleep quality1.27 (0.76)1.44 (0.76)<.001
Sleep latency1.08 (0.9)1.28 (0.97)<.001
Sleep duration1.06 (1.05)1.29 (1.09)<.001
Habitual sleep efficiency0.83 (1.09)1 (1.17).003
Sleep disturbance1.15 (0.54)1.29 (0.59)<.001
Use of sleeping medication 0.23 (0.67)0.33 (0.77).01
Daytime dysfunction1.19 (0.81)1.56 (0.84)<.001

A multiple regression was testes to demonstrated that mobile phone addiction is a factor associated with poor sleep quality as measured by mean PSQI scores even after adjusting for sex, age, and level of studies. The model largely met the assumptions of OLS regression, including linearity, independence, and homoscedasticity. However, the normality test of the residuals did not fully satisfy the assumption of normality. Despite this, we chose to retain the OLS model for several reasons. First, OLS is robust to deviations from normality, particularly when the sample size is large, as was the case in this study. Second, the central limit theorem suggested that the distribution of the residuals would approximate normality with a sufficiently large sample, even if the data were not perfectly normally distributed. Finally, the main goal of this model was to estimate the relationships between variables, and OLS provided unbiased, consistent, and efficient estimates under the assumption of homoscedasticity and linearity, which the model satisfied. Therefore, despite the minor concern regarding normality, the OLS model remained appropriate for the analysis. The model demonstrated the relationship between mobile phone usage and sleep quality among medical students in the study (β=1.4, 95% CI 1.05-1.74; Table 5).

Table 5. Regression analysis of mobile phone addiction impact on sleep disturbance (by Pittsburgh Sleep Quality Index mean scores). Analyses of sleep disturbances predicted by cell phone were controlled for gender, age and educational level (R2=0.06).
VariablesBeta values (95% CI)
Mobile phone addiction1.40 (1.05 to 1.74)a
Sex (female)0.40 (0.06 to 0.74)b
Age0.32 (0.13 to 0.51)a
Level of education (advanced)–0.46 (–0.85 to –0.06)b
Country

Colombia–0.62 (–1.23 to –0.02)b

Ecuador–0.31 (–0.88 to –0.26)

Panama–0.42 (–1.02 to –0.17)

Paraguay–0.17 (–0.79 to –0.44)

Peru–1.41 (–2 to –0.81)a

aP<.001.

bP<.05.


Principal Findings

By the third decade of the 21st century, access to and use of mobile phones has become nearly universal, a reality that includes medical students in Latin America [Izquierdo-Condoy JS, Arias-Intriago M, Nati-Castillo HA, Gollini-Mihalopoulos R, Cardozo-Espínola CD, Loaiza-Guevara V, et al. Exploring smartphone use and its applicability in academic training of medical students in Latin America: a multicenter cross-sectional study. BMC Med Educ. 2024;24(1):1401. [CrossRef] [Medline]24]. This research aimed to explore mobile phone addiction among medical students across 6 Latin American countries, as well as to evaluate their sleep quality and the potential impact of excessive and unhealthy mobile phone use on sleep.

This multicenter study included 1677 undergraduate medical students, revealing a notable predominance of female participants. This finding aligns with recent research indicating that a majority of medical students in Latin America are female [Izquierdo-Condoy JS, Simbaña-Rivera K, Nati-Castillo HA, Cassa Macedo A, Cardozo Espínola CD, Vidal Barazorda GM, et al. How much do Latin American medical students know about radiology? Latin-American multicenter cross-sectional study. Med Educ Online. 2023;28(1):2173044. [FREE Full text] [CrossRef] [Medline]25,Izquierdo-Condoy JS, Montiel-Alfonso MA, Nati-Castillo HA, Saucedo R, Jaramillo-Aguilar DS, Nanjari-Barrientos C, et al. Knowledge, perceptions, and practices on risks and disasters among medical students. A multicenter cross-sectional study in 9 Latin American and Caribbean countries. Adv Med Educ Pract. 2023;14:225-235. [FREE Full text] [CrossRef] [Medline]26]. Nearly 100% of participants reported using a smartphone, a rate comparable with those reported among medical students in other regions [Baticulon RE, Sy JJ, Alberto NRI, Baron MBC, Mabulay REC, Rizada LGT, et al. Barriers to online learning in the time of COVID-19: A national survey of medical students in the Philippines. Med Sci Educ. 2021;31(2):615-626. [FREE Full text] [CrossRef] [Medline]27]. In addition, 94.9% of participants used their devices for academic purposes, a figure higher than in other regions but consistent with global trends favoring the academic use of mobile phones among undergraduate medical students [Machleid F, Kaczmarczyk R, Johann D, Balčiūnas J, Atienza-Carbonell B, von Maltzahn F, et al. Perceptions of digital health education among european medical students: mixed methods survey. J Med Internet Res. 2020;22(8):e19827. [FREE Full text] [CrossRef] [Medline]12,Sharma N, Advani U, Sharma L, Jain M, Sharma K, Dixit A. Pattern of mobile phone usage among medical students. Int J Acad Med. 2019;5(2):118. [CrossRef]28,Singh K, Sarkar S, Gaur U, Gupta S, Adams OP, Sa B, et al. Smartphones and educational apps use among medical students of a smart university campus. Front Commun. 2021;6. [CrossRef]29].

Although smartphones are primarily associated with barrier-free communication through social networks, they also possess numerous tools that are increasingly integrated into academic training, particularly among medical students. However, prolonged and uncontrolled use of these devices can have significant health effects on users [Chase TJG, Julius A, Chandan JS, Powell E, Hall CS, Phillips BL, et al. Mobile learning in medicine: an evaluation of attitudes and behaviours of medical students. BMC Med Educ. 2018;18(1):152. [FREE Full text] [CrossRef] [Medline]30-Ratan ZA, Parrish A, Zaman SB, Alotaibi MS, Hosseinzadeh H. Smartphone addiction and associated health outcomes in adult populations: a systematic review. Int J Environ Res Public Health. 2021;18(22):12257. [FREE Full text] [CrossRef] [Medline]32]. Medical students are uniquely affected by mobile phone addiction and poor sleep quality due to the combination of demanding academic schedules, high stress levels, and the pervasive nature of digital technology. The rigorous nature of medical training often necessitates extensive study hours, leading students to rely heavily on smartphones for quick access to educational materials. This reliance, coupled with the need for social interaction and recreation through the same devices, often results in prolonged and uncontrolled usage.

Despite being regarded as a tool for academic enhancement, approximately one-third (32.5%) of the study population exhibited mobile phone addiction, with rates ranging from 25.5% among Peruvian students to 40.1% among Panamanian students. Comparing addiction rates globally is challenging due to variations in the questionnaires used to assess mobile phone use, addiction, or overuse, such as the Smartphone Addiction Scale (SAS-SV) or the Cell Phone Overuse Scale (COS) [Leow MQH, Chiang J, Chua TJX, Wang S, Tan NC. The relationship between smartphone addiction and sleep among medical students: a systematic review and meta-analysis. PLoS One. 2023;18(9):e0290724. [FREE Full text] [CrossRef] [Medline]33]. For example, Kamal et al [Kamal S, Kamal S, Mubeen SM, Shah AM, Samar SS, Zehra R, et al. Smartphone addiction and its associated behaviors among medical and dental students in Pakistan: a cross-sectional survey. J Educ Health Promot. 2022;11:220. [FREE Full text] [CrossRef] [Medline]34] reported a 48% addiction rate among Pakistani medical and dental students using a similar instrument, while other studies found addiction rates ranging from 10.7% among Iranian medical students [Mohammadbeigi A, Absari R, Valizadeh F, Saadati M, Sharifimoghadam S, Ahmadi A, et al. Sleep quality in medical students; the impact of over-use of mobile cell-phone and social networks. J Res Health Sci. 2016;16(1):46-50. [FREE Full text] [Medline]35] to 34.4% among first and second-year medical students in Srinagar, India [Nowreen N, Ahad F. Effect of smartphone usage on quality of sleep in medical students. Natl J Physiol Pharm Pharmacol. 2018;8(10):1366. [CrossRef]36]. The questionnaire used in the present study [Basu S, Garg S, Singh MM, Kohli C. Addiction-like behavior associated with mobile phone usage among medical students in Delhi. Indian J Psychol Med. 2018;40(5):446-451. [FREE Full text] [CrossRef] [Medline]21] found that addiction was most commonly characterized by tolerance (using the phone more than expected and considering the usage excessive) and a strong desire to use the phone, particularly for immediate interaction on social networks or phone use even when others are nearby, traits typical of addictive behaviors [Shoukat S. Cell phone addiction and psychological and physiological health in adolescents. EXCLI J. 2019;18:47-50. [FREE Full text] [Medline]37]. Despite the heterogeneity in assessment tools, the body of research underscores the pervasive nature of mobile phone addiction among medical students worldwide, including in Latin America.

Interestingly, this study found no significant demographic variables related to overuse or addiction to mobile phones, such as gender [Nikolic A, Bukurov B, Kocic I, Vukovic M, Ladjevic N, Vrhovac M, et al. Smartphone addiction, sleep quality, depression, anxiety, and stress among medical students. Front Public Health. 2023;11:1252371. [FREE Full text] [CrossRef] [Medline]38,Divya YL, Dampetla S, Manjulatha K, Manikanta, Srikanth. Smart phone use and its effect on quality of sleep in medical students. Int J Acad Med Pharm. 2023;5(6):213-217. [CrossRef]39]. However, there was a concerning relationship between students who did not use mobile phones for academic purposes and higher rates of addiction, potentially due to a preference for leisure activities such as social networking, gaming, or streaming platforms [Yu S, Sussman S. Does smartphone addiction fall on a continuum of addictive behaviors? Int J Environ Res Public Health. 2020;17(2):422. [FREE Full text] [CrossRef] [Medline]40]. In addition, students who reported that their studies negatively affected their rest exhibited higher rates of addiction, suggesting an indirect relationship between mobile phone addiction and poor sleep. This notion is supported by findings showing that students who preferred printed texts for studying had lower addiction rates.

Sleep quality studies have become more standardized with the widespread acceptance of the PSQI. The average PSQI score among students in this study (7.26, SD 3.45) indicated poor sleep quality, considerably higher than scores reported in similar studies, including military medical students (PSQI score=5.78, SD 2.26) [Xu JZ. Correlation study on mobile phone addiction and sleep quality of military medical students. Academic Journal of Second Military Medical University. 2019;12:1389-1392.41], Indian medical students (PSQI score=4.43, SD 2.62) [Divya YL, Dampetla S, Manjulatha K, Manikanta, Srikanth. Smart phone use and its effect on quality of sleep in medical students. Int J Acad Med Pharm. 2023;5(6):213-217. [CrossRef]39], and Iranian medical students (PSQI score=5.38, SD 2.31). Systematic reviews report meta-mean PSQI scores between 5.95 and 6.1 [Leow MQH, Chiang J, Chua TJX, Wang S, Tan NC. The relationship between smartphone addiction and sleep among medical students: a systematic review and meta-analysis. PLoS One. 2023;18(9):e0290724. [FREE Full text] [CrossRef] [Medline]33,Rao WW, Li W, Qi H, Hong L, Chen C, Li C, et al. Sleep quality in medical students: a comprehensive meta-analysis of observational studies. Sleep Breath. 2020;24(3):1151-1165. [CrossRef] [Medline]42]. Poor sleep quality among medical students is well-documented and has been attributed to heavy study loads, irregular schedules, and a preference for study over sleep [Preišegolavičiūtė E, Leskauskas D, Adomaitienė V. Associations of quality of sleep with lifestyle factors and profile of studies among Lithuanian students. Medicina (Kaunas). 2010;46(7):482-489. [FREE Full text] [Medline]43,Almojali AI, Almalki SA, Alothman AS, Masuadi EM, Alaqeel MK. The prevalence and association of stress with sleep quality among medical students. J Epidemiol Glob Health. 2017;7(3):169-174. [FREE Full text] [CrossRef] [Medline]44]. In this study, students from private universities and women exhibited worse sleep quality, a trend previously observed in other research [Xu JZ. Correlation study on mobile phone addiction and sleep quality of military medical students. Academic Journal of Second Military Medical University. 2019;12:1389-1392.41].

There was a significant and consistent association between mobile phone addiction and poor sleep quality, with addicted students scoring higher across all PSQI dimensions (subjective sleep quality, sleep latency, sleep duration, habitual sleep efficiency, sleep disturbances, use of sleep medication, and daytime dysfunction) compared with those without addiction (P<.05). Regression analyses revealed a global association between mobile phone addiction and diminished sleep quality, even after adjusting for sex, age, and educational level (β=1.4; 95% CI 1.05-1.74; P<.001). This association has been widely evidenced in previous studies of medical students across different countries and academic levels [Leow MQH, Chiang J, Chua TJX, Wang S, Tan NC. The relationship between smartphone addiction and sleep among medical students: a systematic review and meta-analysis. PLoS One. 2023;18(9):e0290724. [FREE Full text] [CrossRef] [Medline]33,Mohammadbeigi A, Absari R, Valizadeh F, Saadati M, Sharifimoghadam S, Ahmadi A, et al. Sleep quality in medical students; the impact of over-use of mobile cell-phone and social networks. J Res Health Sci. 2016;16(1):46-50. [FREE Full text] [Medline]35,Nikolic A, Bukurov B, Kocic I, Vukovic M, Ladjevic N, Vrhovac M, et al. Smartphone addiction, sleep quality, depression, anxiety, and stress among medical students. Front Public Health. 2023;11:1252371. [FREE Full text] [CrossRef] [Medline]38,Divya YL, Dampetla S, Manjulatha K, Manikanta, Srikanth. Smart phone use and its effect on quality of sleep in medical students. Int J Acad Med Pharm. 2023;5(6):213-217. [CrossRef]39,Xu JZ. Correlation study on mobile phone addiction and sleep quality of military medical students. Academic Journal of Second Military Medical University. 2019;12:1389-1392.41,Boonluksiri P. Effect of smartphone overuse on sleep problems in medical students. The Asia Pacific Scholar. 2018;3(2):25-28. [CrossRef]45].

The findings of this study offer several plausible explanations for the observed association between mobile phone addiction and poor sleep quality. Smartphones facilitate a wide range of activities, including gaming, streaming, and social media use, all of which compete for users’ limited time and attention, often displacing sleep. Social media platforms, in particular, are deliberately designed to capture and retain user engagement through features such as “infinite scroll,” notifications, direct messaging (DMs), and interaction metrics like likes, follows, and shares [Bhargava HK. Infinite Scroll: Addiction by Design in Information Platforms. School of Management University of California Davis; 2023. URL: https://www.teis-workshop.org/papers/2023/Digital_Addiction_and_Advertising.pdf [accessed 2025-01-07] 46,Rixen JO, Meinhardt LM, Glöckler M, Ziegenbein ML, Schlothauer A, Colley M, et al. The loop and reasons to break it: investigating infinite scrolling behaviour in social media applications and reasons to stop. Proc ACM Hum-Comput Interact. 2023;7(MHCI):228. [CrossRef]47]. These features create an attention-driven ecosystem where users are incentivized to remain active, with their engagement monetized for advertising purposes [Bhargava HK. Infinite Scroll: Addiction by Design in Information Platforms. School of Management University of California Davis; 2023. URL: https://www.teis-workshop.org/papers/2023/Digital_Addiction_and_Advertising.pdf [accessed 2025-01-07] 46].

In addition, the blue light emitted by smartphones has been widely recognized as a disruptor of circadian rhythms [Oh JH, Yoo H, Park HK, Do YR. Analysis of circadian properties and healthy levels of blue light from smartphones at night. Sci Rep. 2015;5:11325. [FREE Full text] [CrossRef] [Medline]48-West KE, Jablonski MR, Warfield B, Cecil KS, James M, Ayers MA, et al. Blue light from light-emitting diodes elicits a dose-dependent suppression of melatonin in humans. J Appl Physiol (1985). 2011;110(3):619-626. [FREE Full text] [CrossRef] [Medline]50]. Artificial light exposure, particularly at night, delays the release of melatonin, the hormone responsible for regulating sleep-wake cycles, exacerbating sleep disturbances. Among medical students, this effect is particularly concerning due to their already irregular schedules and high stress levels [Belsare V, Tekade M, Munghate SC, Belsare H. Effect of sleep and smart phone on serum melatonin level in first year medical students. Int J Adv Med. 2020;7(7):1121. [CrossRef]51-Shrivastava A, Saxena Y. Effect of mobile usage on serum melatonin levels among medical students. Indian J Physiol Pharmacol. 2014;58(4):395-399. [Medline]53]. The combination of attention-capturing smartphone apps and blue light exposure likely contributes to prioritizing phone use oversleep, providing a compelling explanation for the current study’s findings.

This study highlights a critical issue, emphasizing the dual impact of mobile phones on the present and future of academic medical training [Gavali MY, Khismatrao DS, Gavali YV, Patil KB. Smartphone, the new learning aid amongst medical students. J Clin Diagn Res. 2017;11(5):JC05-JC08. [FREE Full text] [CrossRef] [Medline]54]. While these devices provide significant benefits, including portable and digital access to textbooks, scientific articles, and practical tools such as video content, infographics, and podcasts [Izquierdo-Condoy JS, Arias-Intriago M, Nati-Castillo HA, Gollini-Mihalopoulos R, Cardozo-Espínola CD, Loaiza-Guevara V, et al. Exploring smartphone use and its applicability in academic training of medical students in Latin America: a multicenter cross-sectional study. BMC Med Educ. 2024;24(1):1401. [CrossRef] [Medline]24,Spicer JO, Coleman CG. Creating effective infographics and visual abstracts to disseminate research and facilitate medical education on social media. Clin Infect Dis. 2022;74(Suppl_3):e14-e22. [CrossRef] [Medline]55-Franz A, Oberst S, Peters H, Berger R, Behrend R. How do medical students learn conceptual knowledge? High-, moderate- and low-utility learning techniques and perceived learning difficulties. BMC Med Educ. 2022;22(1):250. [FREE Full text] [CrossRef] [Medline]57], heir use also presents risks. These resources can enhance knowledge acquisition, even in resource-limited settings like Latin America. However, decision-makers, including university institutions and educators, must be cognizant of the potential negative consequences of mobile phone use in academic environments. These include cross-device addiction, indirect effects on sleep quality, and other physical and mental health challenges.

The broader implications of these findings extend beyond sleep disturbances. Poor sleep quality and mobile phone addiction can significantly impair cognitive function, emotional regulation, and physical health, which are vital for medical students' academic success and future professional practice. Sleep deprivation and distractions caused by addiction may hinder students' ability to learn effectively, retain critical information, and perform competently in clinical settings, ultimately impacting patient care.

Addressing these challenges requires urgent intervention. Institutions should integrate sleep education into medical curricula, emphasizing its importance for cognitive performance and overall well-being. Behavioral strategies, such as implementing “digital detox” periods or encouraging the use of apps that monitor and limit screen time, can help students manage their smartphone use. Furthermore, counseling and support services tailored to stress management and time optimization can address the underlying causes of overuse and improve sleep hygiene.

Limitations

This study has several limitations that should be acknowledged. First, the survey was conducted online, which may have introduced a sampling bias, favoring medical students with easier access to technology or greater familiarity with online platforms. In addition, the reliance on self-reported data poses the risk of social desirability bias, where participants may exaggerate their academic use of smartphones or provide responses they perceive as socially acceptable.

The subjective sleep assessments used in this study, specifically the PSQI, are practical, cost-effective, and widely used in population-based research due to their ease of administration and scalability. However, subjective measures are inherently limited by recall bias and participants’ ability to accurately evaluate their sleep habits. In contrast, objective sleep assessment methods, such as actigraphy and polysomnography, provide direct and measurable data on sleep parameters and are considered more precise. These objective tools often reveal discrepancies compared with subjective assessments, as personal perceptions may lead to overestimation or underestimation of sleep duration or quality. Nevertheless, objective methods may fail to account for psychological factors influencing perceived sleep quality, which subjective tools can capture.

In this study, the reliance solely on subjective measures, such as the PSQI, represents a limitation. This approach may not fully reflect the complexity of sleep patterns or detect potential clinical sleep disturbances. Future research should consider integrating objective assessments to complement and validate self-reported sleep data, providing a more comprehensive understanding of sleep behaviors. Furthermore, the cross-sectional design of this study precludes the establishment of causality between mobile phone addiction and poor sleep quality. It remains unclear whether academic mobile phone use contributes to addiction and reduced sleep quality, or if academically successful students inherently use smartphones more frequently and experience shorter sleep durations.

Finally, while the study included participants from 6 Latin American countries, the findings may not be universally generalizable across the entire region due to cultural, economic, and educational differences. Future studies should aim to include more diverse populations to enhance the external validity of the results.

Conclusions

In conclusion, this study reveals a substantial prevalence of mobile phone addiction among medical students from 6 Latin American countries, affecting approximately one-third of the sample. In addition, the overall sleep quality of student participants was found to be poor, as indicated by a mean PSQI score higher than previously reported. Findings suggest that using mobile phones for studying can indirectly contribute to poorer sleep quality by diverting attention to other activities during study sessions. This underscores the dual nature of mobile technology, which can serve both educational and recreational purposes, each with differing impacts on the lives and health of students. Importantly, we identified a significant association between mobile phone addiction and poor sleep quality. Overall, this study confirms the widespread academic integration of mobile phones among medical students in Latin America and highlights the significant need for strategies to address the use of these devices in academia and their potential impact on health and academic success.

Conflicts of Interest

None declared.

Multimedia Appendix 1

Checklist for Reporting Results of Internet E-Surveys (CHERRIES).

DOCX File , 18 KB

  1. Forecast number of mobile devices worldwide from 2020 to 2025 (in billions)*. Statista; 2024. URL: https://www.statista.com/statistics/245501/multiple-mobile-device-ownership-worldwide/ [accessed 2024-04-28]
  2. Morgan C. Draw Your Phone: The Cellphone as an Intimate, Everyday Artefact. Newland. Teaching and Learning the Archaeology of the Contemporary Era Bloomsbury Publishing; 2023:101.
  3. De-Sola Gutiérrez J, Rodríguez de Fonseca F, Rubio G. Cell-phone addiction: a review. Front Psychiatry. 2016;7:175. [FREE Full text] [CrossRef] [Medline]
  4. Naeem Z. Health risks associated with mobile phones use. Int J Health Sci (Qassim). 2014;8(4):V-VI. [FREE Full text] [Medline]
  5. Zirek E, Mustafaoglu R, Yasaci Z, Griffiths MD. A systematic review of musculoskeletal complaints, symptoms, and pathologies related to mobile phone usage. Musculoskelet Sci Pract. 2020;49:102196. [CrossRef] [Medline]
  6. Westerman R, Hocking B. Diseases of modern living: neurological changes associated with mobile phones and radiofrequency radiation in humans. Neurosci Lett. 2004;361(1-3):13-16. [CrossRef] [Medline]
  7. Exelmans L, Van den Bulck J. Bedtime mobile phone use and sleep in adults. Soc Sci Med. 2016;148:93-101. [CrossRef] [Medline]
  8. White AG, Buboltz W, Igou F. Mobile phone use and sleep quality and length in college students. International Journal of Humanities and Social Science. 2011;1(18):51-58.
  9. Ai S, Ye S, Li G, Leng Y, Stone KL, Zhang M, et al. Association of disrupted delta wave activity during sleep with long-term cardiovascular disease and mortality. J Am Coll Cardiol. 2024;83(17):1671-1684. [CrossRef] [Medline]
  10. Addo PNO, Mundagowa PT, Zhao L, Kanyangarara M, Brown MJ, Liu J. Associations between sleep duration, sleep disturbance and cardiovascular disease biomarkers among adults in the United States. BMC Public Health. 2024;24(1):947. [FREE Full text] [CrossRef] [Medline]
  11. Almutairi H, Alsubaiei A, Abduljawad S, Alshatti A, Fekih-Romdhane F, Husni M, et al. Prevalence of burnout in medical students: a systematic review and meta-analysis. Int J Soc Psychiatry. 2022;68(6):1157-1170. [CrossRef] [Medline]
  12. Machleid F, Kaczmarczyk R, Johann D, Balčiūnas J, Atienza-Carbonell B, von Maltzahn F, et al. Perceptions of digital health education among european medical students: mixed methods survey. J Med Internet Res. 2020;22(8):e19827. [FREE Full text] [CrossRef] [Medline]
  13. Li S, Feng N, Cui L. Network analysis of social anxiety and problematic mobile phone use in Chinese adolescents: a longitudinal study. Addict Behav. 2024;155:108026. [CrossRef] [Medline]
  14. Seoane HA, Moschetto L, Orliacq F, Orliacq J, Serrano E, Cazenave MI, et al. Sleep disruption in medicine students and its relationship with impaired academic performance: a systematic review and meta-analysis. Sleep Med Rev. 2020;53:101333. [CrossRef] [Medline]
  15. Rozgonjuk D, Saal K, Täht K. Problematic smartphone use, deep and surface approaches to learning, and social media use in lectures. Int J Environ Res Public Health. 2018;15(1):92. [FREE Full text] [CrossRef] [Medline]
  16. Thapa K, Lama S, Pokharel R, Sigdel R, Rimal SP. Mobile phone dependence among undergraduate students of a medical college of eastern Nepal: a descriptive cross-sectional study. JNMA J Nepal Med Assoc. 2020;58(224):234-239. [FREE Full text] [CrossRef] [Medline]
  17. Mengi A, Singh A, Gupta V. An institution-based study to assess the prevalence of Nomophobia and its related impact among medical students in Southern Haryana, India. J Family Med Prim Care. 2020;9(5):2303-2308. [FREE Full text] [CrossRef] [Medline]
  18. Copaja-Corzo C, Aragón-Ayala CJ, Taype-Rondan A, Nomotest-Group N. Nomophobia and its associated factors in peruvian medical students. Int J Environ Res Public Health. 2022;19(9):5006. [FREE Full text] [CrossRef] [Medline]
  19. Kaya F, Bostanci Daştan N, Durar E. Smart phone usage, sleep quality and depression in university students. Int J Soc Psychiatry. 2021;67(5):407-414. [CrossRef] [Medline]
  20. Herrell C, Foster S. Can't stop won't stop: problematic phone use, sleep quality, and mental health in U.S. graduate students. J Am Coll Health. 2024;28:1-7. [CrossRef] [Medline]
  21. Basu S, Garg S, Singh MM, Kohli C. Addiction-like behavior associated with mobile phone usage among medical students in Delhi. Indian J Psychol Med. 2018;40(5):446-451. [FREE Full text] [CrossRef] [Medline]
  22. Buysse DJ, Reynolds CF, Monk TH, Berman SR, Kupfer DJ. The pittsburgh sleep quality index: a new instrument for psychiatric practice and research. Psychiatry Res. 1989;28(2):193-213. [CrossRef] [Medline]
  23. Hita-Contreras F, Martínez-López E, Latorre-Román PA, Garrido F, Santos MA, Martínez-Amat A. Reliability and validity of the Spanish version of the pittsburgh sleep quality index (PSQI) in patients with fibromyalgia. Rheumatol Int. 2014;34(7):929-936. [CrossRef] [Medline]
  24. Izquierdo-Condoy JS, Arias-Intriago M, Nati-Castillo HA, Gollini-Mihalopoulos R, Cardozo-Espínola CD, Loaiza-Guevara V, et al. Exploring smartphone use and its applicability in academic training of medical students in Latin America: a multicenter cross-sectional study. BMC Med Educ. 2024;24(1):1401. [CrossRef] [Medline]
  25. Izquierdo-Condoy JS, Simbaña-Rivera K, Nati-Castillo HA, Cassa Macedo A, Cardozo Espínola CD, Vidal Barazorda GM, et al. How much do Latin American medical students know about radiology? Latin-American multicenter cross-sectional study. Med Educ Online. 2023;28(1):2173044. [FREE Full text] [CrossRef] [Medline]
  26. Izquierdo-Condoy JS, Montiel-Alfonso MA, Nati-Castillo HA, Saucedo R, Jaramillo-Aguilar DS, Nanjari-Barrientos C, et al. Knowledge, perceptions, and practices on risks and disasters among medical students. A multicenter cross-sectional study in 9 Latin American and Caribbean countries. Adv Med Educ Pract. 2023;14:225-235. [FREE Full text] [CrossRef] [Medline]
  27. Baticulon RE, Sy JJ, Alberto NRI, Baron MBC, Mabulay REC, Rizada LGT, et al. Barriers to online learning in the time of COVID-19: A national survey of medical students in the Philippines. Med Sci Educ. 2021;31(2):615-626. [FREE Full text] [CrossRef] [Medline]
  28. Sharma N, Advani U, Sharma L, Jain M, Sharma K, Dixit A. Pattern of mobile phone usage among medical students. Int J Acad Med. 2019;5(2):118. [CrossRef]
  29. Singh K, Sarkar S, Gaur U, Gupta S, Adams OP, Sa B, et al. Smartphones and educational apps use among medical students of a smart university campus. Front Commun. 2021;6. [CrossRef]
  30. Chase TJG, Julius A, Chandan JS, Powell E, Hall CS, Phillips BL, et al. Mobile learning in medicine: an evaluation of attitudes and behaviours of medical students. BMC Med Educ. 2018;18(1):152. [FREE Full text] [CrossRef] [Medline]
  31. Montagni I, Donisi V, Tedeschi F, Parizot I, Motrico E, Horgan A. Internet use for mental health information and support among European university students: The e-MentH project. Digit Health. 2016;2:2055207616653845. [FREE Full text] [CrossRef] [Medline]
  32. Ratan ZA, Parrish A, Zaman SB, Alotaibi MS, Hosseinzadeh H. Smartphone addiction and associated health outcomes in adult populations: a systematic review. Int J Environ Res Public Health. 2021;18(22):12257. [FREE Full text] [CrossRef] [Medline]
  33. Leow MQH, Chiang J, Chua TJX, Wang S, Tan NC. The relationship between smartphone addiction and sleep among medical students: a systematic review and meta-analysis. PLoS One. 2023;18(9):e0290724. [FREE Full text] [CrossRef] [Medline]
  34. Kamal S, Kamal S, Mubeen SM, Shah AM, Samar SS, Zehra R, et al. Smartphone addiction and its associated behaviors among medical and dental students in Pakistan: a cross-sectional survey. J Educ Health Promot. 2022;11:220. [FREE Full text] [CrossRef] [Medline]
  35. Mohammadbeigi A, Absari R, Valizadeh F, Saadati M, Sharifimoghadam S, Ahmadi A, et al. Sleep quality in medical students; the impact of over-use of mobile cell-phone and social networks. J Res Health Sci. 2016;16(1):46-50. [FREE Full text] [Medline]
  36. Nowreen N, Ahad F. Effect of smartphone usage on quality of sleep in medical students. Natl J Physiol Pharm Pharmacol. 2018;8(10):1366. [CrossRef]
  37. Shoukat S. Cell phone addiction and psychological and physiological health in adolescents. EXCLI J. 2019;18:47-50. [FREE Full text] [Medline]
  38. Nikolic A, Bukurov B, Kocic I, Vukovic M, Ladjevic N, Vrhovac M, et al. Smartphone addiction, sleep quality, depression, anxiety, and stress among medical students. Front Public Health. 2023;11:1252371. [FREE Full text] [CrossRef] [Medline]
  39. Divya YL, Dampetla S, Manjulatha K, Manikanta, Srikanth. Smart phone use and its effect on quality of sleep in medical students. Int J Acad Med Pharm. 2023;5(6):213-217. [CrossRef]
  40. Yu S, Sussman S. Does smartphone addiction fall on a continuum of addictive behaviors? Int J Environ Res Public Health. 2020;17(2):422. [FREE Full text] [CrossRef] [Medline]
  41. Xu JZ. Correlation study on mobile phone addiction and sleep quality of military medical students. Academic Journal of Second Military Medical University. 2019;12:1389-1392.
  42. Rao WW, Li W, Qi H, Hong L, Chen C, Li C, et al. Sleep quality in medical students: a comprehensive meta-analysis of observational studies. Sleep Breath. 2020;24(3):1151-1165. [CrossRef] [Medline]
  43. Preišegolavičiūtė E, Leskauskas D, Adomaitienė V. Associations of quality of sleep with lifestyle factors and profile of studies among Lithuanian students. Medicina (Kaunas). 2010;46(7):482-489. [FREE Full text] [Medline]
  44. Almojali AI, Almalki SA, Alothman AS, Masuadi EM, Alaqeel MK. The prevalence and association of stress with sleep quality among medical students. J Epidemiol Glob Health. 2017;7(3):169-174. [FREE Full text] [CrossRef] [Medline]
  45. Boonluksiri P. Effect of smartphone overuse on sleep problems in medical students. The Asia Pacific Scholar. 2018;3(2):25-28. [CrossRef]
  46. Bhargava HK. Infinite Scroll: Addiction by Design in Information Platforms. School of Management University of California Davis; 2023. URL: https://www.teis-workshop.org/papers/2023/Digital_Addiction_and_Advertising.pdf [accessed 2025-01-07]
  47. Rixen JO, Meinhardt LM, Glöckler M, Ziegenbein ML, Schlothauer A, Colley M, et al. The loop and reasons to break it: investigating infinite scrolling behaviour in social media applications and reasons to stop. Proc ACM Hum-Comput Interact. 2023;7(MHCI):228. [CrossRef]
  48. Oh JH, Yoo H, Park HK, Do YR. Analysis of circadian properties and healthy levels of blue light from smartphones at night. Sci Rep. 2015;5:11325. [FREE Full text] [CrossRef] [Medline]
  49. Wahl S, Engelhardt M, Schaupp P, Lappe C, Ivanov IV. The inner clock-Blue light sets the human rhythm. J Biophotonics. 2019;12(12):e201900102. [FREE Full text] [CrossRef] [Medline]
  50. West KE, Jablonski MR, Warfield B, Cecil KS, James M, Ayers MA, et al. Blue light from light-emitting diodes elicits a dose-dependent suppression of melatonin in humans. J Appl Physiol (1985). 2011;110(3):619-626. [FREE Full text] [CrossRef] [Medline]
  51. Belsare V, Tekade M, Munghate SC, Belsare H. Effect of sleep and smart phone on serum melatonin level in first year medical students. Int J Adv Med. 2020;7(7):1121. [CrossRef]
  52. Randjelović P, Stojiljković N, Radulović N, Ilić I, Stojanović N, Ilić S. The association of smartphone usage with subjective sleep quality and daytime sleepiness among medical students. Biological Rhythm Research. 2018;50(6):857-865. [CrossRef]
  53. Shrivastava A, Saxena Y. Effect of mobile usage on serum melatonin levels among medical students. Indian J Physiol Pharmacol. 2014;58(4):395-399. [Medline]
  54. Gavali MY, Khismatrao DS, Gavali YV, Patil KB. Smartphone, the new learning aid amongst medical students. J Clin Diagn Res. 2017;11(5):JC05-JC08. [FREE Full text] [CrossRef] [Medline]
  55. Spicer JO, Coleman CG. Creating effective infographics and visual abstracts to disseminate research and facilitate medical education on social media. Clin Infect Dis. 2022;74(Suppl_3):e14-e22. [CrossRef] [Medline]
  56. Krumm IR, Miles MC, Clay A, Carlos Ii WG, Adamson R. Making effective educational videos for clinical teaching. Chest. 2022;161(3):764-772. [FREE Full text] [CrossRef] [Medline]
  57. Franz A, Oberst S, Peters H, Berger R, Behrend R. How do medical students learn conceptual knowledge? High-, moderate- and low-utility learning techniques and perceived learning difficulties. BMC Med Educ. 2022;22(1):250. [FREE Full text] [CrossRef] [Medline]


CHERRIES: Checklist for Reporting Results of Internet E-Surveys
COS: Cell Phone Overuse Scale
DM: direct message
Gen Z: generation Z
ICD-10: International Statistical Classification of Diseases, Tenth Revision
OLS: ordinary least squares
PSQI: Pittsburgh Sleep Quality Index
SAS-SV: Smartphone Addiction Scale-Short Version


Edited by S He; submitted 16.05.24; peer-reviewed by S Ghazi, J Bartwal; comments to author 14.10.24; revised version received 13.12.24; accepted 14.12.24; published 10.02.25.

Copyright

©Juan S Izquierdo-Condoy, Clara Paz, H A Nati-Castillo, Ricardo Gollini-Mihalopoulos, Telmo Raul Aveiro-Róbalo, Jhino Renson Valeriano Paucar, Sandra Erika Laura Mamami, Juan Felipe Caicedo, Valentina Loaiza-Guevara, Diana Camila Mejía, Camila Salazar-Santoliva, Melissa Villavicencio-Gomezjurado, Cougar Hall, Esteban Ortiz-Prado. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 10.02.2025.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Journal of Medical Internet Research (ISSN 1438-8871), is properly cited. The complete bibliographic information, a link to the original publication on https://www.jmir.org/, as well as this copyright and license information must be included.